230例围手术期患者预防性应用抗菌药调查与分析

Survey and Analysis of Preventive Antimicrobial Administration in 230 Patients During Perioperative Pe-riod

目的:了解围手术期病例抗菌药应用情况,评价其用药合理性。方法:采用回顾性调查方法,对2002年12月～2003年4月,部分外科手术病例应用抗菌药的品种、用药频度、相关费用比、联合用药情况、用药时间、疗效以及药物不良反应等进行调查与分析。结果:230例围手术期患者抗菌药物的应用率为100％,涉及32个品种、8 595例/次;人均抗菌药费用为1 183.5元,疗程21.89天;手术切口甲级愈合224例,总药费与抗菌药费之比为1:0.41。结论:应加强围手术期抗菌药应用管理。

OBJECTIVE:To find out the situation of the use of antimicrobials in perioperative patients and to evaluate the rationality of use.METHODS: To make a survey of the use of antimicrobials in 230 surgical patients during the period Dec. 2002 - Apr. 2004, and to evaluate the kinds, frequency, cost - effectiveness ratios, combined administration, course, effectiveness and drug adverse react ions. RESULTS: 100 percent patients had received antimicrobials involving 32 kinds of drug and 8 595 case - time.The cost of consumption of antimicrobials per case was 1 183.5 yuans.The average therapeutic course was 21.89 days.The operation incisions healed by first intention in 230 cases.The cost ratios of total drugs and antimicrobials was 1 : 0.41 .CONCLUSION:The supervision of using antimicrobials in perioperative period must be reinforced.