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反义寡核苷酸在恶性肿瘤研究中的现状和展望 被引量:8

The Present and Outlook of Antisense Oligodeoxynucleotide in Malignant Tumor
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出处 《肿瘤防治研究》 CAS CSCD 2004年第3期182-184,共3页 Cancer Research on Prevention and Treatment
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  • 2[2]Yuen A, Advani R, Fisher G,et al.A phase I/II trial of ISIS 3521, an antisense inhibitor of protein kinase C alpha, combined with carboplatin and paclitaxel in patients with non-small cell lung cancer[J]. Am Soc Clin Oncol, 2000,19(6): 459-461.
  • 3[3]Webb A, Cunningham D, Cotter F,et al. BCL-2 antisense therapy in patients with non-Hodgkin lymphoma[J].Lancet, 1997,349(9059):1137-1141.
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  • 5[5]Chi KN, Gleave ME, Klasa R,et al.A phase I dose-finding study of combined treatment with an antisense Bcl-2 oligonucleotide (Genasense) and mitoxantrone in patients with metastatic hormone-refractory prostate cancer[J]. Clin Cancer Res,2001, 7(12):3920-3927.
  • 6[6]C.M.Rudin, G.A.Otterson, A. M. Mauer, et al. A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer[J]. Annals of Oncology, 2002,13(4):539-545.
  • 7[7]Banerjee D. Genasense (Genta Inc).Curr Opin Investig Drugs[J]. 2001, 2(4):574-580.
  • 8[8]Fennell DA, Corbo MV, Dean NM,et al.In vivo suppression of Bcl-XL expression facilitates chemotherapy-induced leukaemia cell death in a SCID/NOD-Hu model[J].Br J Haematol, 2001,112(3):706-713.
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