期刊文献+

The effect of taurine to NOS vigor in hippocampus of rat induced lead lesion

The effect of taurine to NOS vigor in hippocampus of rat induced lead lesion
下载PDF
导出
摘要 Objective: To study taurine resist lead impact ability of learning and memory. Methods: Using NADPH - dhistochemistry method to study the quantity change of the rat's NOS positive neuron in hippocampus , the rat in experi-ment sections which are feeded with distinct dosage lead acetate in drinking (0.02, 0.2g/L) and feed contain distinctdosage taurine (5, 10g/kg). Results: Taurine could increase NOS positive neuron quantity obviously in hippocampus ofrat induced lead lesion. Conclusion: Taurine could resist lead impact ability of learning and memory obviously. Objective: To study taurine resist lead impact ability of learning and memory. Methods: Using NADPH - d histochemistry method to study the quantity change of the rat's NOS positive neuron in hippocampus , the rat in experiment sections which are feeded with distinct dosage lead acetate in drinking (0.02, 0.2g/L) and feed contain distinct dosage taurine (5, 10g/kg) . Results: Taurine could increase NOS positive neuron quantity obviously in hippocampus of rat induced lead lesion. Conclusion: Taurine could resist lead impact ability of learning and memory obviously.
出处 《武警医学院学报》 CAS 2004年第1期3-6,共4页 Acta Academiae Medicinae CPAPF
关键词 牛磺酸 大鼠 海马 NOS 阳性 神经元数目 学习 记忆 Taurine Lead Hippocampus NOS Learning and memory
  • 相关文献

参考文献11

  • 1[1]WANG YL, Bacli Gang. Modern labour hygiene [M]. Beijing:The people sanitation publishing house, 1994. 46 - 85.
  • 2[2]Huxtable RJ. Physiological Actions of Taurine [J]. Physiol Rev,1992, 72: 101-161.
  • 3[3]Yamada K, Noda Y, Nakayama S, et al. Role of nitric oxide in learing and memory and in monoamine metabolism in the rat brain[J]. BrJPharmacol, 1995, 115 (5): 852-858.
  • 4[4]Zhou M, Small SA, Kandel ER, et al. Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus [J]. Science, 1993, 260 (5116): 1949- 1950.
  • 5[5]Thompon RF, Kim JJ. Memory system in the brain and licalization of a memory [J]. Proc Natl Acad Sci USA, 1996, 93:13438.
  • 6[6]Platt B, Carpenter DO, Busselberg D, et al. Aluminum impairs hippocampallong-term potentiation in rats in vitro and in vivo [J].Exp Neurol, 1995, 134 (1): 73-86.
  • 7[7]Bernabeu R, de Stein ML, Fin C, et al. Role of hippocampal NO in the acquisition and consolidation of inhibitory avoidance learning [J]. Neuroreport, 1995, 6: 1498-1500.
  • 8[8]Stewart WF, Schwartz BS, Simon D, et al. Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers [J]. Neurology, 1999, 52 (8): 1610 -1617.
  • 9[9]Murphy KJ, Regan CM. Low-level lead exposure in the early postnatal period results in persisting neuroplastic deficits associated with memory consolidation [J]. J Neurochem, 1999, 72 (5):2099 - 2104.
  • 10[10]Quinn MR, Harris CL. Lead inhibits Ca2+-stimulated nitric oxide synthase activity from rat cerebellum [ J]. Neurosci Lett,1995, 196 (1-2): 65-68.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部