MEBT/MEBO在浅Ⅲ度烧伤创面愈合过程中的组织学观察

Histological observation of the healing course of superficial third degree burn wounds treated with MEBT/MEBO

目的 :从组织学角度验证MEBT/MEBO治疗浅Ⅲ度烧伤创面 ,能够达到生理性再生修复 ,及其不同时期组织学变化。方法 :分别于MEBT/MEBO治疗后 1天、 3天、 7天、 2 0天、及 30～ 4 0天创面愈合后取标本 ,常规光镜、电镜制样 ,进行光镜、透射电镜对创面各期内进行组织形态观察。结果 :浅Ⅲ度烧伤创面经MEBT/MEBO正规治疗 ,历经早期真皮组织变性坏死 ,中后期棘细胞、纤维母细胞、毛细血管增生等阶段 ,最后再生修复的上皮组织形态可以恢复正常。结论 :MEBT/MEBO治疗浅Ⅲ度烧伤创面再生修复属完全性生理再生 ,其愈合后创面组织形态可以恢复正常。

Objective: To verify the physiological regeneration effect of MEBT/MEBO in the treatment of superficial 3 rd degree burn wounds and to observe histological changes at different stages. Method: Specimens were taken on days 1,3, 7 and 20 after starting the treatment, and on 30 and 40 days after wound healing and were observed under optical and electron microscopes. Result: Superficial 3 rd degree burn wounds after standardized MEBT/MEBO treatment, the dermal tissue had necrotic changes at the early stage, and at the middle and later stages, prickle cells, fibroblasts and micro-vessels had hyperplastic changes, and finally the morphology of the regenerated epithelial tissue turned normal. Conclusion: Superficial 3 rd degree burn wounds after standardized MEBT/MEBO treatment regenerated physiologically, the morphology of the healed wound tissue was normal.