TNF相关的凋亡诱导配体及其受体与恶性黑素瘤的凋亡
TNF Related Apoptosis Induced Ligand and the Receptor in the Apoptosis of Malignant Melanoma
摘要
TNF相关的凋亡诱导配体 (TRAIL)及其受体 (TRAILR)是近年来很受关注的一组凋亡相关分子 ,目前发现的该家族成员包括TRAIL和它的四个受体。恶性黑素瘤细胞表面表达TRAIL和TRAILR ,并可以被其诱导凋亡。由于TRAIL仅能诱导转染细胞或肿瘤细胞凋亡 ,对正常的细胞没有细胞毒作用 ,因此在恶性黑素瘤的治疗中具有良好的应用前景。
出处
《中国皮肤性病学杂志》
CAS
北大核心
2003年第4期279-281,共3页
The Chinese Journal of Dermatovenereology
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