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咪唑斯汀(皿治林)治疗急性荨麻疹疗效观察 被引量:6

Observation on the Therapeutic Effects of Mizolastine in the Treatment for Acute Urticaria
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摘要 目的 探讨咪唑斯汀 (皿治林 )治疗急性荨麻疹的临床疗效。方法 对 91例急性荨麻疹予口服咪唑斯汀 10mg ,留院观察治疗后 1h、2h药物起效时间和各项症状指标积分变化情况。 结果 药物起效时间在 0 .5~ 1.0h的患者占 5 0 .0 % ;治疗后 1h有效率为 64 .83 % ,治疗后 2h为 91.2 0 % ;患者的瘙痒、风团数量、红晕程度及症状积分值较治疗前分别有明显下降 ,治疗前后评分比较差异均有显著性 (P均 <0 .0 1)。临床观察期间未发现明显副作用。结论 该药安全可靠 ,为治疗急性荨麻疹新的有效药物。
出处 《中国皮肤性病学杂志》 CAS 北大核心 2003年第4期J001-J002,共2页 The Chinese Journal of Dermatovenereology
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  • 1[1]Benavides J,Schoemaker H,Dana C,et al.In vivo and in vitro interaction of the novel selective histamine H1 receptor antagonist mizolastine with H1 receptors in the rodent[J].Arzneimittelforschung,1995,45(5): 551-558.
  • 2[2]Levrier J.Duval D,Prouteau M,et al.Anti-anaphylactic activity of the novel selective histamine H1 receptor antagonist mizolastine in the rodent [ J ].Arzneimittelforschung,1995,4-5 (5): 559-568.
  • 3[3]Sudo K,Nagai K,Yamada N.Inhibitory effects of mizolastine on 5-1ipoxygenase[J] Jpan Pharmacol Ther,1998,26(Suppl):155-157.
  • 4[4]Yamada N,Furiayama K.Inhibitory effects of mizolastine on the release of mediators and antagonistic effects against mediators[J].Jpan Pharmacol Ther,1998,26(Suppl): S131-S138.
  • 5[5]Michel L,Murrieta-Aguttes M,Jean-Louis F,et al.Humoral and cellular responses to histamine and pollen allergen in a skin chamber model: effect of mizolastine[J].Ann allergy Asthma Immunol,2000,85 ( 1 ): 64-69.
  • 6[6]Pichat P,Angel I,Arbbila S.Anti-inflammatory properties of mizolastine after oral administration on arachidonic acid-induced cutaneous reaction in the rat[J].Arzneimittelforschung,1998,48(2):173-178.
  • 7[7]Baroody FM,Naclerio RM.Antiallergic effects of HI-receptor antagonists[J].Allergy,2000,55(Suppl 64): 17-27.
  • 8[8]Kontou-Fili K.Clinical advantages of dual activity in urticaria[J].Allergy,2000,55(Suppl 64): 28-33.
  • 9[1]Scadding GK,Tasman AJ,Murrieta-Aguttes,et al.Mizolastine is effective and tolerated in long-term treatment of perennial allergic rhinoconjunctivitis riperex study group[J].Clin Med Res,1999,27:273-285.
  • 10[2]Pichat P,Angel I,Arbilla S.Anti-inflammatory properties of mizolastine after oral administration on arachidonic acid-induced cutaneous reaction in the rat[J].Arzneimittelforschung,1998,48:173-178.

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