糖尿病患者非体外循环冠状动脉旁路移植术围手术期临床分析

Off-pump coronary artery bypass in the diabet ic patient-Perioperative clinical analysis

目的 探讨糖尿病对非体外循环冠状动脉旁路移植术 (OPCAB)的影响。 方法 2 51例患者接受OPCAB ,其中糖尿病患者 (DM组 ) 71例 ,非糖尿病患者 (NDM组 ) 180例。单变量统计分析两组的术前危险因素和术后并发症。 结果 两组患者术后在监护室的时间 [DM组 (2 .4± 0 .3 )d ;NDM组 (2 .4± 0 .3 )d ;P =0 .3 86]、胸部切口并发症 (DM组 :5.7% ;NDM组 :3 .9% ;P =0 511)等方面差异无显著意义 ,两组患者术后严重并发症 :脑卒中 (DM组 :2 .8% ;NDM组 :1.7% ;P =0 .62 3 )、肾功能衰竭血液透析 (DM组 :2 .8% ;NDM组 :0 .5% ;P =0 .194)、心肌梗死 (DM组 :0 % ;NDM组 :0 5% ;P =1.0 0 0 )及死亡率 (DM组 :2 .8% ;NDM组 :1.1% ;P =0 .680 )差异无显著意义。 结论 糖尿病患者经适当控制病情以后 ,OPCAB可以如同非糖尿病患者一样安全地实施。

ObjectiveDiabetes is an independent risk factor for coronary artery bypasss grafting(CABG). Off pump coronary artery bypasss (OPCAB) experience in 251 cases was reviewed to determine whether diabetes wou ld be applicable in OPCAB procedures.MethodsConsecutive 251 patients underwent OPCAB over 12 month period. This study included 71 diebetic patients (DM group) and 180 nondiabetic patients (NDM group). Preoperative v ariables were compared between the two groups by univariate analysis.R esultsNo differences were found regarding the length of stay in cardio intensive care unit [DM group(2.4±0.3)d; NDM group (2.4±0.3) d;P=0. 386], and sternal complication (DM group: 5.7%;NDM group: 3.9%;P=0.511) . In hospital complications were as follows: death rate(DM group: 2.8%; NDM gr oup: 1.1%; P=0.680); stroke (DM group: 2 8%; NDM group: 1 7%; P=0 623 ); hemofiltratioin renal failure (DM group: 2.8%; NDM group: 0.5%; P=0.194); myocardial infarction(DM group: 0%; NDM group: 0.5%;P=1.000); blood using were more frequent in DM group comparied with NDM group (P=0.111). ConclusionOPCAB in diabetic patients is as safe as in non diabetic patients.