新型双苯甲酰基脲类化合物的合成(英文)

Synthesis of Novel Bis-benzoylphenylurea Chitin Inhibitors

从原料百菌清出发 ,经过氟交换、氨解、水解、脱羧和酰化反应 ,合成得到 1 2个新型双苯甲酰基脲类几丁质抑制剂衍生物 ,总收率超过 3 0 %～5 0 %。

Twelve novel bis-benzoylphenylurea chitin inhibitor derivatives have been synthesized in over 30～50% yield from chlorothalonil via sequential fluorine exchange, nitrile hydrolysis, decarboxylation and acylation reactions.