3-(2-氯-4-三氟甲基苯氧基)-N-芳基苯甲酰胺的合成与植物生长调节活性

Synthesis and Plant Growth Regulation Activity of 3-(2-Chloro-4-trifluoromethylphenoxy)-N-aryl benzamides

为考察对苯氧基苯甲酰胺类化合物的生物活性特点,以3-(2-氯-4-三氟甲基苯氧基)苯甲酸和氯化亚砜为原料先合成得到酰氯,再与取代芳胺反应,得到了8个新的标题化合物。通过IR、1HNMR、MS和元素分析对该系列化合物的结构进行了确证。采用小麦芽鞘法和黄瓜子叶法测定了它们对小麦和黄瓜的植物生长调节活性,结果表明:在10μg/g浓度下,所有化合物均显示出促进小麦芽鞘伸长的活性,其中3b的促进率为27.08%,高于对照药剂吲哚乙酸IAA(10.10%);而化合物3d、3h则显示了很强的促进黄瓜生根的活性,在10μg/g浓度下,促进率分别为66.66%和55.55%,显著高于IAA(12.5%)。

Eight new compounds of title compounds were (synthesized) by the reaction of aryl amines with 3-(2-chloro-4-trifluoromethylphenoxy) benzoyl chloride which was prepared from (3-(2-chloro)-4-trifluoromethylphenoxy) benzoic acid and thionyl chloride. They were (confirmed) by IR, ()~1H NMR, MS and elemental analysis. Their plant growth regulating activities were tested by wheat coleoptile and cucumber cotyledon test. At the concentration of 10 μg/g, all of the (compounds) exhibited stimulating activities to the growth of wheat (coleoptile.)The stimulating (activity) of 3b(27.08%) was higher than that of β-indoleacetic(IAA)(10.10%). The stimulating (activities) to the growth of (cucumber) root of compounds 3d(55.55%) and 3h(66.66%) were (higher) than that of IAA(12.5%) at the concentration of 10 μg/g.