摘要
以苯酚为原料,在甲醇镁溶液的作用下,得到苯酚镁,蒸馏出大部分甲醇后,再以甲苯为溶剂, 在95℃下与多聚甲醛反应生成水杨醛的镁盐,酸化后得到水杨醛。反应时间2小时,收率达81%。
Deprotonation of phenol using magnesium methoxide,followed by distillative removal of free methanol and addition of paraformaldehyde results in ortho-specific magnesium-mediated formylation to give the corresponding Salicylaldehyde magnesium salts,from which the Salicylaldehyde can be isolated by acidic work-up in yield 81%.
出处
《精细化工原料及中间体》
2004年第4期30-32,共3页
Fine Chemical Industrial Raw Materials & Intermediates
