摘要
目的 探讨注意缺陷多动障碍 (attentiondeficithyperactivitydisorder,ADHD)儿童和正常儿童在主动和被动注意状态下 ,事件相关电位N1、P2、N2、P3各波的异同。 方法 采用病例对照方法 ,对 30例ADHD儿童和 30例正常儿童 ,分别在被动和主动注意状态下进行经典的听觉Oddball模式事件相关电位研究。 结果 ①在不同注意状态下 ,ADHD组靶刺激N2、P3潜伏期显著长于对照组 (P <0 .0 5 ) ;波幅差异无显著意义。②两组儿童随注意程度的增加P3波幅也显著升高 ,但ADHD组Fz点波幅变化不显著。③两次测试的波幅增幅比较 ,两组儿童间差异无显著意义。④ADHD组的计数成绩显著低于对照组。
Objective To investigate the difference of event-related potentials of ADHD children and normal controls in passive and active tasks. Methods ERP was elicited by a simple auditory Oddball task in 30 ADHD children and 30 normal controls.In the passive attention,the children were told to read a story and ignore auditory stimuli,and in the active attention,to count the rare tones. Results ①The N2P3 latencies of ADHD children were significantly longer than that of controls in two tasks,however no difference was found in amplitude between the two groups.②Both ADHD subjects and controls showed an enhanced P3 from the passive task to the active task,except for ADHD children in Pz.③P3 ampitudes increased to the same extent in both groups from the passive task to the active task.④ ADHD subjects made significantly fewer correct counting than the normal controls. Conclusion The prolonged latencies of N2P3 may have the implication of cognitive function deficit of ADHD children.
出处
《中国校医》
2004年第2期109-111,共3页
Chinese Journal of School Doctor