天津市20a间胃恶性肿瘤发病分析

Incidence of gastric malignant tumors during the past 20 years in Tianjin

目的:为探讨天津市近20 a胃恶性肿瘤的发病趋势及特点, 为临床和病理医生提供有价值的诊断思路. 方法:材料来自天津医科大学总医院及第二医院病理科1981/2000年外科病理检查胃恶性肿瘤资料,以Microsoft excel表格形式存储.列统计图表显示胃恶性肿瘤20 a检出趋势.并分别计算各型恶性肿瘤的构成比和平均确诊年龄, 对不同类型,不同性别的胃恶性肿瘤患者年龄进行方差分析(ANOVA)和t检验(或u检验). 结果:20 a来胃恶性肿瘤无论男、女检出数均呈逐年递增趋势,2000年达到顶峰;检出男3 121例,女1 323例,男女之比为2.36:1.前10 a为1 923例,后10 a为2 542例, 前后10 a之比为0.76:1.其中胃癌所占比例最大96.19%, 确诊年龄也最大(58.3岁).组织学类型中以腺癌最多;男女两性确诊年龄不同,男性(59.8岁)高于女性(54.5岁). 结论:胃恶性肿瘤尤其胃癌的发生与环境危险因素的增多和人口老龄化等有关,所以,做好早期防治工作任重而道远.

AIM: To study the incidence and its tendency of gastric malignant tumors during the past 20 years in Tianjin and to provide information for clinicians and pathologists. METHODS: The data of gastric malignant tumors were collected from the General Hospital and the Second Hospital of Tianjin Medical University. The data from 1981/2000 were stored in Excel. The tendency of gastric malignant tumors during the past 20 years was showed by statistical graph. Tthe proportion and average ages of every type of malignant tumors were calculated and analyzed by T-test or ANOVA. RESULTS: The incidence of gastric malignant tumors was increasing in both male and female during the past 20 years and reached the top in 2 000. The cases of male were 3121 and female, 1323. The relative ratio of male to female was 2.36 .' 1. The cases in the previous 10 years were 1 923 and the latter 10 years were 2 542. The relative ratio was 0.76 : 1. Gastric cancer was 96.19%, its proportion was the highest and the average age was also oldest (58.3 years). Adenocarcinoma was the main histo-logical type. The average ages of male and female patients were different. CONCLUSION: The pathogenesis of gastric malignant tumors is associated with aged population and environmental pollution. Early diagnosis and treatment is critcal to the patients' prognosis.