2-硫代-3-芳基-5-苯基亚甲基-4-咪唑啉二酮衍生物的有效合成新方法

A new efficient synthesis method of 2-thio-3-aryl-5-phenylmethylidene-4-imidazolidinones

研究了应用烯基膦亚胺与二硫化碳、芳伯胺的串联aza Wittig反应 ,来合成 2 硫代 3 芳基 5 苯基亚甲基 4 咪唑啉二酮衍生物的有效新方法。提出了可能的环化反应机理 ,探讨了所合成化合物的成环反应条件和波谱性质。生成的环化产物均为新的化合物 ,其结构经元素分析、IR、1HNMR和MS确证。

Thio-3-aryl-5-phenylmethylidene-4-imidazolidinones were synthesized via tandem aza-Wittig reaction of vinyliminophosphorane,carbon disufide and aromatic primary amines.A possible mechanism for the cyclization reaction was put forward,and the spectral properties and the condition for cyclization of the synthesized compounds were researched.All the cyclized products are new,and their structures were confirmed by elemental analysis,IR,MS and 1HNMR .