咀嚼无糖口香糖对含漱蔗糖溶液后牙菌斑原位pH值的影响

Effect of chewing sugar-free gum after sucrose challenge on dental plaque pH in situ

目的 通过对牙菌斑原位pH值变化的动态监测 ,观察咀嚼无糖口香糖对牙菌斑原位pH值的影响。方法 采用受试者自身对照的临床试验方法 ,选择 16名健康成人志愿者为受试者 ,年龄 2 3～ 32岁 ,其中男性 6名 ,女性 10名。首先测定受试者 4 8h菌斑的静止pH值 ,以及受试者用10 %蔗糖溶液含漱 1min后在 5、10、2 0和 30min时菌斑的pH值 ,取得受试者的Stephan曲线作为基线对照 ;而后观察咀嚼两种益达无糖口香糖对含漱 10 %蔗糖溶液后菌斑pH值变化的影响。菌斑原位pH值的测定采用pH微电极接触法在口内直接测量。结果 含漱 10 %蔗糖溶液后立即开始咀嚼无糖口香糖可使菌斑pH值在各检测时间点 (含漱 10 %蔗糖溶液后 5、10、2 0和 30min)均维持在静止pH水平 ,无明显下降 ;含漱 10 %蔗糖溶液后在 5min时开始咀嚼无糖口香糖则使菌斑pH值从含漱蔗糖溶液后 5min时的 5 .5 9迅速回升至 10min时的 6 .98。结论 受到蔗糖攻击后 ,咀嚼无糖口香糖可迅速缓冲菌斑的酸性产物 ,升高菌斑pH值。

Objective To evaluate the effect of chewing sugar-free gum after sucrose challenge on dental plaque pH in situ. Methods 16 healthy volunteers aged 23-32 years were screened as subjects. The pH of 48-hour dental plaque was measured using a Beetrode pH microelectrode when subjects chewed Extra sugar-free gum after sucrose challenge. Results Dental plaque pH maintained at resting plaque pH when immediately chewed sugar-free gum after sucrose challenge. Chewing sugar-free gum at 5 min after sucrose challenge, dental plaque pH was raised from 5.59 (measured at 5 min after sucrose challenge) to 6.98 (measured at 10 min after sucrose challenge). Conclusions Chewing sugar-free gum after sucrose challenge can neutralize organic acid produced by bacteria in dental plaque and rapidly rise plaque pH.