云南蜱媒病毒的血清流行病学研究

Study on Serological Epidemiology of Tick-borne Viruses in Yunnan

1988～1990年,我们采集了10地、州(县)1813份不明热病人及健康人血清,126份高黎贡山鼠类和山羊血清,以及13种鸟类和恒河猴血清462份,采用微量血凝抑制法、间接免疫荧光法和SPA组化法,检测森林脑炎、科萨努尔森林病,波瓦生、兰加特和新疆出血热病毒抗体。结果发现,除蒙自县外,其它9地区人群中均有上述抗体。其中森林脑炎和科萨努尔森林病病毒抗体阳性率较高的地区集中在泸水,阳性率分别为30.55%和27.17%。从泸水高黎贡山捕获的鼠类和山羊血清也含较高的森林脑炎抗体(50%)。波瓦生抗体以丽江地区较高,为25.66%;新疆出血热抗体阳性率较高的是西双版纳,39.17%。另外,鸟类和恒河猴也不同程度地携带蜱媒病毒抗体,从抗体的分布可见,这些疾病呈地区性分布。

In 1988-1990, 1813 sera samples of the health people and unknown fever patients, 126 sera samples of the rodents and sheep captured at Gaoligongshan mountain as well as 416 sera samples of rhesus and 13 species of birds collected in 10 prefectures(counties)were detected by HI, IFIT and HRPSPA. The results showed that there were Russian summer- spring encephalitis (RSSE), Kyasanur forest disease (KFD), Powassan (POW), Langat (LGT) and Xingjiang hemorrhagic fever (XHF) viruses antibodies in 9 prefectures (counties) except Menzi. Among them, RSSE and FD antibodies were higher in Lushui than in the other area, positive rate were 30.55% (11/36) and 27.17%(10/36) respectively. Positive rate of POW antibodies were 25.55& (39/152) in Lijiang. Positive rate of XHF antibodies was the highest in Xishuanbanna, 39.17% (47/120). Tickborne viruses antibodies were also carried by birds, rhesus and bats. These diseases distributed over in the district because it may relate to the factor of nature and climate.