摘要
目的 :对新生儿红细胞葡萄糖 - 6 -磷酸脱氢酶 (G - 6 -PD)缺陷症进行临床分析。方法 :用四氮唑蓝 (NBT)定量法测定新生儿红细胞G - 6 -PD活性。结果 :男女发病率有一定差异 ,男性明显多于女性 ;男女患者G - 6 -PD活性、黄疸程度和血红蛋白均值无显著性差异 (P >0 0 5 )。结论 :新生儿红细胞G - 6 -PD缺陷症的发病可以由感染、氧化性药物、缺氧等因素诱发 ,也可以没有任何诱因 ,男女患者在G - 6 -PD活性、病情程度上没有差异。
Objective:To analyze neonatal glucose-6-phosphate dehydrogenase(G-6-PD)deficiency deeply and clinically.Methods:NBT was used to detect activities of G-6-PD.Results:Incidence in male was higher than that in female.The ratio of male to female was 1.78.No differences between male and female in activities of G-6-PD and serum bilirubin and hemoglobin(P>0.05).Conclusion:Neonatal G-6-PD deficiency could induced by infection,oxidation drugs,hypoxia or so,and could happen without any inducement.Difference excited between male and female in incidence but no differences in disease degree and activities of G-6-PD.
