丙型肝炎患者肿瘤坏死因子和白细胞介素6的水平及意义

Tumour necrosis factor and Interleukine 6 in patient with Hepatitis C virus

本文采用肿瘤坏死因子单克隆抗体的 ELISA 法检测了72例丙型肝炎、丙型肝炎合并乙型肝炎及乙型肝炎患者血浆肿瘤坏死因子并测定其细胞诱生白细胞介素6的生物活性.结果发现,患者肿瘤坏死因子及白细胞介素6水平增高,尤以丙型肝炎病毒感染患者为甚.并且,患者肿瘤坏死因子和白细胞介素6呈显著相关.这一结果表明,肿瘤坏死因子和白细胞介素6在丙型肝炎病毒感染的致病原理中可能有一定意义.

Tumout necrosis factor(TNF)and Interleukine 6(IL-6)Level of 72 patients with HCV,HCV and HBV,HBV were easured.We found that TNF and IL-6 Level were increasde in patients withHCV,HCV and HBV.There was a positive elationship between TNP and IL-6.The results suggustthat TNF and IL-6 probale involved in patngenicithy in HCV nfections.