粉体粒径对碳酸化羟基磷灰石水泥固化时间和压缩强度的影响

The Effect of Different Diameters Powder on Setting Time and Compressive Stress of Carbonated Hydroxyapatite Cement

目的 检测不同粉体粒径对碳酸化羟基磷灰石水泥 (carbonatedhydroxyapatitecement,CHC)的固化时间和压缩强度的影响 ,为其修复骨缺损提供理论基础。方法 采用研磨和超细粉体技术制备 4 0 0目、6 0 0目和超细粉体粒径的CHC干粉 ,检测不同粉体粒径对CHC固化时间和压缩强度变化。结果 超细CHC干粉平均粒径为3.10 9μm ,比表面积为 2 .2 88m2 /cm3 ,在 37℃、10 0 %湿度条件下CHC固化时间随粉体粒径减小而缩短 ,而固化后压缩强度随粉体粒径缩小而升高 ,超细粉体CHC初凝时间 3min ,终凝时间 8min ,最终固化后压缩强度 (5 1.0 4 2± 3.72 8)MPa。结论 超细CHC具有原位固化性能 ,固化时间合理 ,压缩强度高 。

Objective To investigate the effect of different diameter powder on setting time and compressive stress of carbonated hydroxyapatite cement (CHC). Methods 400, 600 meshes and ultramicropowder were prepared by grind and ultramicropowder methods, and the effects on setting time and compressive stress were observed. Results The average diameter of ultramicropowder was 3.109μm, and the specific surface area was 2.288m 2/cm 3. Under 37℃ and 100% humidity, the setting time shorten along with the reduced diameter powder, and the compressive stress increased along with the reduced diameter powder. The initial setting time of ultramicropowder CHC was 3 minutes, and the final setting time was 8 minutes. The final compressive of ultramicropowder CHC stress was (51.042±3.728)MPa. Conclusion The results showed ultramicropowder CHC could solidify in situ with rational setting time and high compressive stress, which adapt to clinical application.