摘要
目的:了解住院患者的合理用药情况。方法:应用VFP6.0系统处理数据、PASS软件进行相互作用分析、“医院患者信息查询系统”查阅病历。结果:调查涉及1207例患者7314条单日医嘱,平均用药6种,涉及药物739种,出现频率排名依次为水、电解质平衡调节类、循环系统、抗感染类、消化系统、激素及其相关药、血液系统、维生素与矿物质类药物;存在药物-药物间相互作用204例、药物-食物间相互作用235例;当用药品种为1～4种、5～9种、>10种时,存在药物不良相互作用的比例分别为3%、22.8%、42.62%。结论:为防止发生药物不良相互作用,临床应注意合理用药,尽量减少用药品种,避免不必要的联合用药。
Objective:To understand current use of drugs for inpatients.Met ho d:Prescription Automatic Screening System(PASS)was used for investigation of possible drug interactions.Results:7314prescriptions of1207inpatients were analysed,and739drugs were involved in total,6drugs per prescription o n average.The frequency of drug administration was as follows in order:drugs regulating water and electrolytes,cardiovascular drugs,antimicrobials,gastro-intestinal drugs,hormones,drugs affecting the blood,vitamins and minerals. There were drug-drug interactions in204cases and drug-food ones in235cas es.The incidence of adverse reactions were3%,22.8%and42.62%respec tively for1-4,5-9and over10drugs in combined use.Conclusion:In order to avoid adverse reactions the prescribing should follow the principle of ration al drug use,and the number of the drugs should be prescribed as few as possible .
出处
《药物不良反应杂志》
2004年第2期88-91,共4页
Adverse Drug Reactions Journal
