洋金花和极化液联用治疗冠心病所致病态窦房结综合征临床研究

Combination of Flos Datarae and Pelarlaed Liquid for the Treatment of Sick Simms Syndrome due to Coromary Heart Diaesse

目的:探讨联合应用洋金花和葡萄糖-胰岛素-钾(GIK)极化液治疗病态窦房结综合征(SSS)的疗效。方法:100例SSS患者随机分为两组,治疗组68例,洋金花散剂0.3g,口服,每日1次,10%葡萄糖500 ml+胰岛素8u+10%氯化钾10mL静脉滴注,每日1次,共计14 d;对照组32例仅行上述极化液静脉滴注治疗。于治疗前和治疗后分别行24 h动态心电图及食管电生理检查。结果:治疗后,治疗组平均心率、24 h总心率和对照组相比差异有显著性(P<0.01);窦房结恢复时间(SNRT)、校正后窦房结恢复时间(cSNRT)和窦房传导时间(SACT)和对照组相比有显著性差异(P<0.01)。结论:联合应用洋金花和CIK极化液治疗病态窦房结综合征是一种安全有效的方法。

To determine the therapeutic effects of combination of floa daturae and glucose-inaulin-kalium( GIK) polarized liquid on the treatment of sick sinus syndrome(SSS). Methods: 100 patients of SSS were divided into two groups. Flos daturae and GIK polarised liquid were administrated to 68 cases as treatment group.GIK polarised liquid was given by intravenous to 32 cases as control group. E-lectrocardiogram and esophageal-electrophyaiological examination were performed before and after treatment. Results: After treatment,the avenge heart rate,total heart rate of treatment group were significantly higher than control group.The sinus node recovery time(SNRT) ,corrected SNRT and sinus atrium conduction time( SACT) were all significantly shorter than control group. Conclusion:Combination of flos dalune and GIK polarized liquid is an effective strategy for the treatment of sick sinus syndrome.