薄层层析法监测2-乙酰氨基-3,4,6-三乙酰葡萄糖的合成

MONITORING OF 2-AETYLAMINO-3,4,6-TRI ACETYL GLUCOPYRANOSE BY THIN LAYER CHROMATOGRAPHY

用薄层层析法对2 乙酰氨基 3,4,6 三乙酰葡萄糖合成过程中所涉及的样品进行了分离分析,选择优化出最佳展开剂体系为V正己烷∶V乙酸乙酯=1∶1。在此条件下,反应原料、反应中间体和反应产物可以得到有效地分离,能够较好地指示反应进程。

Thin layer chromatography was used to identify and analyze the products in the preparation of 2-aetylamino-3,4,6-tri acetyl glucopyranose. The optinum spreading solvent system is n-hexane∶ethyl acetate=1∶1 (V/V). The reactants, intermediates and products were separated effectively.