酶法合成月桂酸单甘油酯

Enzymatic Synthesis of Decanoic Acid Monoglycerides

采用脂肪酶直接对月桂酸和甘油进行酯化,考察了反应温度、水份、反应物摩尔比及酶用量对月桂酸单甘油酯合成的影响,确定了酶促反应进行的最适反应温度为60oC,反应物摩尔比为1:1,酶用量为0.5%,最终产物含量可达70%以上,后处理过程大大简化.

Decanoic acid monoglyceride was synthesized by esterification of glycerol with decanoic acid. The effects of molar ratio of glycerol to fatty acid, reaction temperature, content of water and enzyme ratio over total weight on the reaction were studied. The optimum reaction conditions were confirmed to be 50oC, mole ratio of substrates 1:1, enzyme ratio over total weight 0.5%, and the purity of monoglyceride product in the reaction mixture was more than 70%. The advantage of the process includes simple procedure, high product content, and gentle reaction conditions.