广州地区发热幼儿中人类疱疹病毒7的检测

Detection of human herpesvirus 7 infection in infants of Guangzhou with febrile diseases

目的:检测广州地区发热幼儿中人类疱疹病毒7(HHV-7)的感染状况,从而了解HHV-7感染在此类疾病中的病原学意义。方法:采用n-PCR法检测患儿血浆中的HHV-7DNA。结果:在发热疾病组中血浆HHV-7DNA阳性率为18 0%,而在作为对照的健康组及非发热疾病组的阳性率分别为0和5 4%,发热疾病组与对照组间比较有显著性差异。结论:在广州地区的发热幼儿中HHV-7感染具有一定的病原学意义。

Aim: To detect the human herpesvirus 7(HHV-7) infection rate in Guangzhou's infants with febrile diseases and then to elucidate the pathological significance of HHV-7 infection in this kind of disease. Methods: n-PCR was used to detect the HHV-7 DNA in the plasma of the infant patients. Results: The HHV-7 positivity rates in the febrile diseases group and in the 2 control groups, the healthy controls and the other diseases without febrile, were respectively 18.0%, 0.0% and 5.4%. The difference between the febrile diseases group and the controls was significant. Conclusion:The HHV-7 infection can cause with infants' febrile diseases in Guangzhou.