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明胶酶及其调节机制与头颈部鳞癌的侵袭转移 被引量：2

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摘要 头颈部鳞癌的侵袭和转移是当前治疗所面临的一大难题,也是治疗失败和患者死亡的主要原因。明胶酶由于能降解基底膜的主要成分Ⅳ型胶原,与头颈部鳞癌的侵袭转移关系密切。目前对明胶酶的研究重点已从在肿瘤中的异常表达转移到研究它们的调节机制和作用靶点,主要目的不仅是为诊断和预后寻找新的生物学标记,更重要的是为探索头颈部鳞癌个体化治疗提供新的途径。本文就明胶酶及其调节机制与头颈部鳞癌的侵袭转移作一综述。
作者 覃纲 黎万荣
机构地区 四川泸州医学院附属医院耳鼻咽喉头颈外科
出处 《国外医学（耳鼻咽喉科学分册）》 2004年第2期112-115,共4页 Foreign Medical Sciences(Section of Otolray Ngology Foreign Medical)
关键词 明胶酶 调节机制 头颈部鳞癌 侵袭转移
分类号 R739.91 [医药卫生—肿瘤]
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参考文献22

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同被引文献11

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国外医学（耳鼻咽喉科学分册）
2004年 第2期

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