多巴酚丁胺和硝普钠联合治疗难治性心力衰竭的疗效观察45例

The Forty-five Curativeeffect and Observation Cases of Intractable Heart Failure Combined Treatment Using Dobutamine and Sodium Nitroprusside

目的 观察多巴酚丁胺和硝普钠联合治疗难治性心力衰竭的疗效。方法 难治性心力衰竭45例除常规抗心力衰竭药物治疗以外,加用多巴酚丁胺2～5ug/kg·min及硝普钠100ug/kg·min始渐加量持续静点72小时。结果 两药合用临床总有效率为93.3%,对心脏功能有明显改善,未见不良反应。结论 多巴酚丁胺和硝普钠联合治疗难治性心力衰竭安全、有效,无明显毒副作用。

Objective To observe the clinical effect of Dobutamine combined with Sodium nitroprus-side for treatment of intractable heart failure.Methods 40 paients with intractable heart failure wereenrolled.Besides routine medicines, Dobutamine(2ug/kg·min) and Sodium nitroprusside (100ug/kg·min)were gradually continuous utended in 72 hours; Result The total effective rate was 93.3%.Cardiacfunction was obviously improved and no adverse reaction happened.Conclusion Dobutamine combined withSodium nitroprusside dobutamine is effective and safe, no obvious side effect for treatment ofintractable heart failure.