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急性白血病患者血清TNF-α和SIL-2R的检测及临床意义 被引量:1

Clinical Significance of Tumor Necrosis Factor ( and Soluble Interleukin 2 receptor in Patients With Acute Leukemia
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摘要 目的 为探讨急性白血病 (AL)患者血清肿瘤坏死因子α(TNF -α)和可溶性白细胞介素 2受体 (SIL -2R)水平及其临床意义。方法 应用ELISA法测定AL患者血清TNF -α和SIL -2R水平。结果 ALL患者血清TNF -α和SIL -2R水平明显增高 (P <0 .0 1)。结论 血清中TNF -α和SIL -2R水平的增高可能和AL的发生发展有关 ,测定血清TNF -α和SIL -2水平对观察AL的病情和疗效有一定的临床价值。 Objective To investigate the clinical significance of tumor necrosis α (TNFα) and soluble interleukin 2 receptor (sIL-2R)in patients with acute leukemia (AL). Methods The levels of TNFα and sIL-2R were detected by ELISA. Results The levels of TNFα and sIL-2R of patients with AL were higher than that in healthy persons (P<0.01). Conclusions The levels of TNFα and sIL-2R were related to AL, and they were valuable for evaluating patients' condition and curative effect.
作者 袁宇宁 杨勤
出处 《实用全科医学》 2004年第3期193-194,共2页 Applied Journal Of General Practice
关键词 急性白血病 血清TNF-Α SIL-2R 血清肿瘤坏死因子Α 诊断 TNF-α sIL-2R Acute leukemia
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  • 1刘平.肿瘤坏死因子在恶性血液病中的作用[J].国外医学(输血及血液学分册),1994,17(4):206-208. 被引量:7
  • 2李大启.肿瘤坏死因子α与白血病的研究进展[J].国外医学(输血及血液学分册),1995,18(1):23-25. 被引量:5
  • 3伍学强,刘少君,席雨人,巢燕语,河南医科大学一附院.ANLL和MDS患者外周血细胞分泌TNFα的研究[J].中华血液学杂志,1996,17(2):89-89. 被引量:7
  • 4罗云萍,黄宗干.IL-6和TNF对白血病细胞的调控作用及意义[J].上海免疫学杂志,1996,16(3):169-172. 被引量:9
  • 5[1]Hoogstraten B,Baker H,Gilbert HS.Serum folate and serum vitamin B12 in patients with malignant hematologic diseases.Cancer Res 1965;25:1933
  • 6[2]Cimino G,Amadori S,Cava MC,et al.Serum IL-2 receptor and TNF-α levels are significantc increasedin acute leukemia patients.Leukemia 1991;5:32
  • 7[3]Beksa CM,Erturk S,Akan H,et al.The clinical correlations of serum tumor necrosis factor-alpha in acute leukemia: a predictor of response and relapae? Leukemia 1993;7:1773
  • 8[4]Zhou MX,Harry W,Lantua M,et al.Effect of TNF-a on the proliferation of leukemic cells from children with Bcell precursor acute lymphoblastic leukemia (Bcp-ALL): studies of primary leukemia cells and Bcp-ALL cell lines.Blood 1991;77:2003
  • 9Katsura K, Park M, Gatanaga M, et al. Identification of proteolytic enzyme which cleaves human P75 TNF receptor in vitro [ J]. Biochem Biophys Res Commun, 1996,222:298 -302.
  • 10Colleen WM, Leah AG, Laughlin KV, et al. Plasma concentrations of soluble tumor necrosis factor receptor I and tumor necrosis factor during cardiopulmonary bypass. [J]. Ann Thorac Surg, 2000,70:1313-1318.

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