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50例散发性乳腺癌患者BRCA1基因的检测 被引量:2

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摘要 应用PCR和直接测序方法检测 5 0例散发性乳腺癌中国汉族患者的BRCA1基因突变情况 ,结果未发现BRCA1基因突变现象。提示散发性乳腺癌中国汉族患者BRCA1基因突变较为罕见 ,与国外报道一致。
出处 《苏州大学学报(医学版)》 CAS 2004年第1期91-92,共2页 Suzhou University Journal of Medical Science
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参考文献5

  • 1[1]Hall JM,Lee MK,Newman B,et al.Linkage of earlyonset familial breast cancer to chromosome,17 q21[J].Science,1990,250:1684.
  • 2[2]Miki Y,Swensen J,Shattuck-Eidens D,et al.A Strong candidate for the breast and ovarian cancer susceptibility gene BRCA1[J].Science,1994,266:66.
  • 3[3]Furteal PA,Liu Q,Shattuck-Fidens D,et al.BRCA1 mutation in primary breast and ovarian carcinoma[J].Science,1994,266:120.
  • 4[4]Ford D,Eston DF,Peto J.Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence[J].Am J Hum Genet,1995,57(6):1457.
  • 5[5]Schwab M,Class A.Savelyeval[J].Cancer Lett, 2002 ,175(1):1~8.

同被引文献18

  • 1甄林林,武正炎,范萍,王萱仪.散发性乳腺癌患者BRCA1基因突变检测[J].南京医科大学学报(自然科学版),2005,25(10):693-696. 被引量:5
  • 2Miki Y,Swensen J,Shattuck-Eidens D,et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCAI[J]. Science, 1994,266(5182):66-71.
  • 3Kawai H, Li H, Churl P, et al. Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells [J]. Oncogene, 2002, 21(50): 7730-7739.
  • 4Karp SE, Tonin PN, Begin LR, et al. Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women[J]. Cancer (Phila.),1997,80(3): 435-441.
  • 5Loman N, Johannsson O,Bendahl PO,et al. Steroid receptors in hereditary breast carcinomas associated with BRCA 1 or BRCA2 mutations or unknown susceptibility genes[J]. Cancer(Phila.), 1998,83(2): 310-319.
  • 6Swisher EM,Sakai W,Karlan BY,et al. Secondary BRCA1 muta-tions in BRCA1-mutate ovarian carcinomas with platinum resis-tance. Cancer Res, 2008,68 : 2581-2586.
  • 7Miki Y,Swensen J,Shattuck ED,et al. A strong candidate for thebreast and ovarian cancer susceptibility gene BRCA1. Science,1994,266(5182):66-70.
  • 8Levy-Lahad E,Friedman E. Cancer risks among BRCA1 andBRCA2 mutation carriers. Br J Cancer,2007,96( 1) : 11-15.
  • 9Gayther AS,Harrington P,Russell P,et al. Rapid detection of re-gionally clustered germ-line BRCA1 mutations by multiplex het-eroduplex analysis. Am J Hum Genet, 1996,58(3) :451-456.
  • 10Radice P. Mutations of BRCA genes in hereditary breast and o-varian cancer. Exp Clin Cancer Res,2002,21(3) :9-12.

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