BIPAP呼吸机治疗COPD合并Ⅱ型呼吸衰竭的应用

BiPAP ventilation therapy for patients suffering from chronic obstructive pulmonary disease (COPD) with respiratory failure

目的 探讨BiPAP呼吸机经鼻罩通气在慢性阻塞性肺疾病 (COPD)合并Ⅱ型呼吸衰竭的临床应用。方法 40例COPD合并Ⅱ型呼吸衰竭患者随机分为两组 ;治疗组应用BiPAP呼吸机 ;对照组采用低浓度鼻导管吸氧。观察两组治疗前、后生命体征变化 ,测定动脉血气分析。资料进行统计学分析。结果 治疗前动脉血气分析pH、PaCO2 、PaO2 两组无统计差异 (p >0 .0 5 ) ;治疗后pH、PaO2 和PaCO2 两组均有统计差异 ;患者气促症状减轻 ,临床症状改善。结论 BiPAP呼吸机可提高COPD患者通气效率 ,改善动脉血气 ,缓解临床症状。

Objective To observe the curetive effect of BiPAP ventilation therapy for patients suffering from chronic obstructive pulmonary disease (COPD) with respiratory failure.Methods 20 patients were treated by BiPAP ventilation as experimental group while other 20 patients treated by general O 2 intake via nose-tube as control group.Results The results of blood-gas examination showed that there was no difficults on two groups before treatment (P>0.05).After treatment ,the pH value,PaCO 2 and PaCO 2 were significantly improved in experimental group with less short-breath symptom.Conclusions BiPAP ventilation therapy is a good nontraumatic method for treating COPD with respiratory failure.