摘要
目的 观察中缝大核 (NRM )内催产素 (OT)对电针镇痛的影响。方法 以钾离子透入法引起大鼠甩尾反应的电流强度 (mA)为痛行为反应指标 ,测定动物痛阈 ,观察NRM内催产素对电针镇痛的影响。结果 NRM内微量注入抗催产素血清后 ,大鼠电针镇痛的效应明显减弱 ;与注射正常兔血清相比 ,有显著性差异。结论 NRM内的催产素在电针镇痛的复杂过程中发挥着一定作用。
Objective To study the effect of Oxytocin(OT)on electroacupuncture analgesia in nucleus raphe magnus(NRM).Methods The potassium iontophoresis induced tail-flick was used to measure the pain threshold.The effet of NRM injection of anti-OT serum (AOTS)on the pain threshold in the rat was investigated.Results Injection of AOTS reduced the electroacupuncture analgesia significantly.Conclusion There results indicate that OT in NRM is involved in electroacupuncture analgesia.
出处
《济宁医学院学报》
2004年第1期6-7,共2页
Journal of Jining Medical University
基金
山东省自然科学基金资助课题 (编号Q98CO112 4)
