降纤酶联合紫外线照射并充氧后自血回输治疗脑梗死的临床观察

Clinical Research of Defibrase Combined with Ultraviolet Radiation Oxygenate Self-blood Transfusion in the Treatment of Cerebral Infarction

目的 :观察降纤酶联合紫外线照射并充氧后自血回输治疗脑梗死的临床疗效及血液流变学的变化。方法 :6 0例脑梗死患者随机分为两组 :①治疗组 :32例 ;②对照组 2 8例。两组患者均采用脱水剂、脑细胞保护剂作常规治疗。在此基础上 ,治疗组加用降纤酶、紫外线照射并充氧后自血回输治疗 ;对照组加用低分子右旋糖酐 +复方丹参治疗。结果 :总有效率 :治疗组为 94 % (30 /32 ) ,对照组为 79% (2 2 /2 8) ,两组比较 ,有极显著性差异 (P <0 .0 1)。治疗组治疗后高切、低切全血粘度、血浆粘度、红细胞压积、全血还原粘度、红细胞变形指数、红细胞刚性指数、纤维蛋白原、血沉均较治疗前明显下降 ,有显著性差异 (P <0 .0 5 )。结论 :采用降纤酶联合紫外线照射并充氧后自血回输治疗脑梗死疗效显著 ,并显著改善血液流变学各项指标 ,是一种较好的治疗方法。

Objective:To observe curative effect of defibrase combined with ultraviolet radiation oxygenate self-blood transfusion in the treatment of patients with cerebral infarction.Methods:Sixty patients with cerebral infarction were divided into treatment group of defibrase combined with ultraviolet radiation oxygenate self blood transfusion and control group.The clinical manifestation and changes of Hemorrheology before and after treatment were observed.Results:The curative rate of treatment group was significantly higher than that of control group( P <0.01).The whole blood viscosity、plasma viscosity、plasma fibrinogen were decreased significantly in the treatment group( P <0.05).Conclusion:Efibrase combined with ultraviolet radiation oxygenate self blood transfusion is significantly effective in treatment of patients with cerebral infarctions.