用力吸气流量在COPD和支气管哮喘中的应用

The Value of Forced Inspiratory Flow in Chronic Obstructive Pulmonary Diseases and Asthma Patients

目的 评价用力吸气流量指标在慢性阻塞性肺疾病 (COPD)和支气管哮喘中价值。方法 观察COPD 80例和支气管哮喘 2 0例在吸入支气管扩张剂后用力吸气流量指标的前后变化。结果 轻度 COPD患者和支气管哮喘患者 FEV1 ,FIV1 ,PEF,PIF,FEF 5 0 % ,FIF 5 0 %指标 ,在吸入支气管扩张剂前后均有明显的差异。但用力吸气流量指标与用力呼气流量指标在统计学无差别。而中、重度 COPD患者 FIV1 %较 FEV1 %有显著差异性。结论 在 COPD中 ,在评价支气管的可逆性方面 ,用力吸气流量具有用力呼气流量同样的效果。甚至在重度 COPD患者中 ,FIV1

Objective To evaluate the value of the forced inspiratory parameters and forced expiratory parameters in the treatment of chronic obstructive pulmonary diseases (COPD) and asthma.Methods Eighty COPD patients were divided into three groups:mild/moderate group (n=20), severe group (n=40) and asthmatic group (n=20). Through inhaling bronchodilators, the responsive effects of these parameters were measured including forced inspiratory vlume in 1s (FIV1), forced expiratory vlume in 1s (FEV1), peak inspiratory flow (PIF), peak expiratory flow (PED), 50% forced inspiratory flow (FIF50%), 50% forced expiratory flow (FEF50%). Results There were obvious improvements in FIF, FEF, PEF, PIF, FIF50% and FEF50% after inhaled bronchodilators for mild and moderate COPD and asthma groups,and there was no significant difference in forced inspiratory paratmeters and forced expiratory parameters (p > 0.05) for severe COPD patients.There were more apparent changes for the rate of FIV1 (p < 0.05) than for FEV1. Conclusion In COPD and asthma patients, forced inspiratory parameters are similar to forced expiratory parameters in evaluating airway reversibility. For severe COPD patients, FIF1% may be more sensible than FEV1%.