期刊文献+

联合免疫抑制疗法治疗类肿瘤型舍格伦综合征的疗效研究 被引量:2

The Evaluation of Immunosuppressors in the Treatment of Tumor-like Sjogren’s Syndrome
下载PDF
导出
摘要 目的 :评价联合免疫抑制疗法在治疗类肿瘤型舍格伦综合征中的临床应用。方法 :临床表现为类肿瘤型的舍格伦综合征患者共 2 2名。免疫抑制剂选用的是强的松和氯喹。根据临床表现 ,将治疗效果分为优、良、差 3级。结果 :强的松和氯喹联合治疗类肿瘤型舍格伦综合征的总有效率可达 95 .5 %。结论 Objective: To evaluate the efficacy of combined immunosuppressors in the treatment of tumor-like Sjogren’s Syndrome. Methods: This research includes 22 female patients. The immunosuppressors are corticosteriod and chloroquine. Results: The results are divided patients into three level, such as excellent, good and bad. It was showed that the efficiency ratio was 95.5%. Conclusions: Therapy with combined immunosuppressors is an effective method in tumor-like Sjogren’s Syndrome.
出处 《口腔医学研究》 CAS CSCD 2004年第2期177-179,共3页 Journal of Oral Science Research
关键词 类肿瘤型 舍格伦综合征 免疫抑制剂 联合用药 诊断标准 自身免疫性疾病 Immunosuppressor Corticosteriod Chloroquine Tumor-like Sjogren’s Syndrome
  • 相关文献

参考文献3

二级参考文献2

共引文献13

同被引文献24

  • 1Zambetti LP, Laudisi F, Licandro G, et al. The rhapsody of NLRPs : master players of inflammation...and a lot more[J]. Immunol Res, 2012,53 ( 1/2/3 ) : 78-90.
  • 2Huang Z, Yu M,Tong S, et al. Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice[J]. J Vet Sci,201d, 15 (2) : 173-177.
  • 3Laudisi F,Spreafico R,Evrard M,et al. Cutting edge:the NLRP3 inflam- masome links complement-mediated inflammation and IL-1β release[J]. J Immunol, 2013,191 (3) : 1006-1010.
  • 4Beynon V, Quintana FJ, Weiner HL. Activated human CD4+CD45RO+ memory T-cells indirectly inhibit NLRP3 inflammasome activation through downregulation of P2X7R signalling [J]. PLoS One, 2012,7 (6) : e39576.
  • 5Asgari E ,Le Friee G ,Yamamoto H ,et al. C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 in- flammasome activation[J]. Blood, 2013,122 (20) : 3473-3481.
  • 6Keyel PA. How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1 [J]. Cytokine ,2014,69(1 ) : 136-45.
  • 7Shin MS, Kang Y, Lee N, et al. U 1-small nuclear ribonucleoprotein acti- vates the NLRP3 inflammasome in human monocytes[J]. J Immunol, 2012, 188 (10) :4769-4775.
  • 8Lupfer C ,Kanneganti TD. The expanding role of NLRs in antiviral imnm- nity[J]. Immunol Rev, 2013,255 ( 1 ) : 13-24.
  • 9Lee HM,Yuk JM ,Kim KH ,et al. Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-l-Syk and p62/SQSTM1 [J]. Imnmnol Cell Bio1,2012,90 (6) :601-610.
  • 10Zhao J,Wang H, Dai C, et al. P2X7 blockade attenuates murine lupus ne- phritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway[J]. Arthritis Rheum, 2013,65 (12) : 3176-3185.

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部