善得定治疗新生儿上消化道出血30例疗效观察

Observe on the effect of sandstain in 30 cases of newborns upper gastrointestinal bemorrhage

目的 :探讨善得定用于新生儿上消化道出血的疗效。方法 :将 2 0 0 0年 1月至 2 0 0 2年 1 2月收住院的 58例新生儿上消化道出血患儿随机分成两组。治疗组 30例在常规止血治疗的同时 ,给予善得定 0 0 2mg 肌注 ,对照组只给于常规止血治疗 ,两组患儿在原发疾病方面无显著差异 (P >0 0 5)。观察两组患儿出血停止 ,出血好转时间。结果 :治疗组患儿出血停止 ,出血好转时间明显短于对照组 ,治疗组 80 %的患儿于用药48小时内出血停止 ,疗效显著 (P <0 0 0 1 )。结论 :善得定治疗新生儿上消化道出血疗效确切 ,值得推广。

Objective:To investigate the curative effect of sandstain in upper gastrointestinal hemorrhage of newborns.Methods:58 cases of the newborns with upper gastrointestinal hemorrhage who had been in hospital form January 2000 to December 2002,randomly were divided into two groups.The therapeutic group,30 cases,with sandsain( 0.02 mg im),and ordinary hemostases.The control group,28 case, with ordinary hemostases only.There are no significant differences between the primary disease of two groups(P>0.05).To observe the time that two groups to stop hemorrhage,straighten up or improve little.Results:The therapeutic group took less time to stop hemorrhage or straighten up than the control group 80% of therapeutic group stopped hemorrhage in 48 hours.Effect is remarkable.Conclusions:The curative effect of sandstain in upper gastrointestinal hemorrhage of newborns is assured.