妊高征患者血清铜锌超氧化物歧化酶含量变化

Change of serum levels of Ca/Zn superoxide dismutase in patients with edema-hypertension-proteinuria syndrome

摘要检测正常晚孕、妊高征患者血清SOD-1含量变化发现:正常妊娠分娩前后无明显变化,轻、中度妊高征与重度妊高征患者呈相反变化,前者产前明显升高,产后降至正常;后者分娩前很低,分娩后回升至正常。重度患者平均动脉压和血清SOD-1含量呈变量关系,两者呈负相关。

Serum levels of Cu/Zn superoxide dismutase (SOD- 1) was determined in normal third trimester pregnant women and in patients with edema hypertension-protein- uria syndrome both before and after term labor. The re- sults showed: 1. Serum levels of SOD-1 did not appear to be significantly different (P<0. 05)between pre- and postdelivery in normal pregnant women. 2. It was signifi- cantly higher in patients with mild and moderate edema- hypertension-proteiuria syndrome than normal pregnant women (P<0. 01). 3. The serum level of SOD-1 was lower in patients with severe edema-hypertension-protein- uria syndrome than normal late pregnant women (P<0. 05). This study suggests that the use of SOD-1 may be important in patients with severe edema-hypertension- proteinuria syndrome.