果糖注射液治疗严重创伤的临床研究

Clinical observation of fructose in treatment of critical trauma

目的 观察 5 %果糖注射液对严重创伤患者的治疗作用及不良反应。方法 将 4 3例严重创伤随机分为试验组和对照组。试验组 2 0例 ,静滴 5 %果糖注射液 ;对照组 2 3例 ,静滴 5 %葡萄糖注射液。比较两组的血糖、肝肾功能、血尿酸、血尿常规的变化。结果 试验组给药后和给药后 2小时血糖均无明显变化 ,对照组给药后血糖出现一过性升高 (P <0 .0 1 ) ,2小时后恢复到给药前水平。结论 果糖注射液用于严重创伤患者的能量补充安全有效 ,且不会引起血糖水平大幅度波动。

Objective To study the effectiveness and safety of fructose in treatment of critical trauma.?Methods?Forty three critical trauma patients were randomly divided into two groups:?group A (n=20)and group B (n=23).?Group A were treated with fructose;?group B were treated with glucose.?Blood sugar,liver and renal functions,blood uric acid,routine test of blood and urine were analysed after treatment.?Results Two hours after treatment,blood sugar was normal in group A,but it rose transiently after treatment(P<0.01)and lasted for 2 hours.?Conclusion Fructose is a safe and effective energy supply for treatment of critical trauma without fluctuation of blood sugar.