摘要
对33例经胃镜检查初步诊断为胃癌的患者进行18FDG-PET(18F脱氧葡萄糖-正电子断层扫描)检查,并经手术和病理证实,胃癌术后随访病例19例,以评价18FDG-PET对胃癌的诊断价值。18FDG-PET对于肿瘤原发病灶诊断准确率97%(32/33),1例假阴性,远处转移准确率100%(6/6)。对于单纯胃局部(主要为第1站)淋巴结转移灵敏度55%(6/11),特异性为100%。改变22%(7/32)的患者治疗方案。19例随访病例中7例PET显示阴性,其中5例随访时间超过2年而未见复发。12例发现局部和/或多发转移,其中锁骨上淋巴结转移4例,肺转移2例,肝转移3例,腹腔淋巴结转移6例,吻合口局部复发3例,骨转移6例。18FDG-PET对胃癌的诊断、分期和疗效监测有很高的价值。
To evaluate the value of ^(18)FDG-PET in the diagnosis and management of patients with gastric carcinoma, 33 patients with potentially gastric carcinoma by endo and 19 patients operated are included. A whole-body FDG-PET is acquired and is evaluated for increased focal uptake. Accuracy is determined by comparing PET with surgical staging. The primary tumour is visualized in 97%(32/33) with PET. Distant metastases are found in six patients(100% 6/6), the sensitivity is 55%(6/11), and the specificity is 100% for local-regional lymph nodes. 22% patients are impacted on the treatment planning. There are 7 PET negative (at least 2 years of 5 patients follow-up) in the 19 patients operated.12 patients have generalized single and/or multiple metastases, 4 clavicle lymph metastasis, 2 lung metastasis, 3 liver metastasis, 6 abdominal lymph metastasis, 3 local recurrence and 6 bone metastasis. ^(18)FDG-PET may be suggest for using in the diagnosis and staging of gastric carcinoma and following-up patients with recurrent gastric carcinoma.
出处
《同位素》
CAS
2004年第1期27-30,共4页
Journal of Isotopes
