^(99)Tc^m(V)-DMSA与^(99)Tc^m-MIBI亲肿瘤显像在诊断甲状腺髓样癌中的对比

Comparison of ^(99)Tc^m (V)-DMSA and ^(99)Tc^m-MIBI Scintigraphy in Medullary Thyroid Carcinoma

对62例甲状腺髓样癌(MTC)患者手术前行SPECT亲肿瘤显像,其中99Tcm(V)-DMSA显像组32例,99Tcm-MIBI显像组30例;并对两组患者早期和延迟影像的定性和半定量分析结果进行比较。结果显示:两种显像方法对MTC原发灶诊断的阳性率无显著性差异(P>0.05),但半定量分析结果显示99Tcm(V)-DMSA对原发灶显像的早期摄取比、延迟摄取比、滞留指数明显高于99Tcm-MIBI显像,差异有显著性(P<0.001),提示99Tcm(V)-DMSA显像更具有优越性。

SPECT scintigraphy is used in 62 patients with medullary thyroid carcinoma(MTC), which are divided into two groups: 32 patients by ^(99)Tc^m (V)-DMSA and 30 patients by ^(99)Tc^m-MIBI. The qualitative analysis and half quantitative analysis are performed to the early and delayed images. Comparing the resuls with two groups, there is no difference in the masculine rate of MTC primary focus, but the results of ^(99)Tc^m (V)-DMSA scintigraphy is obviously larger than ^(99)Tc^m-MIBI by half quantitative analysis. The results show that the ^(99)Tc^m (V)-DMSA scintigraphy is more predominant than the ^(99)Tc^m-MIBI scintigraphy in the diagnosis accuracy of MTC metastasis focus. The diagnosis and clinical value of ^(99)Tc^m(V)-DMSA scintigraphy may be superior to ^(99)Tc^m-MIBI in MTC primary focus and metastasis focus before surging for MTC patients.