肠道水疗对治疗急性胰腺炎疗效的观察

Effects and Mechanism of Whole Gut Washout on Acute Pancreatitis in Human

目的:观察肠道水疗对急性胰腺炎患者的治疗效果,并试图阐明其作用机制。方法:治疗组病人除常规治疗外,同时给予隔日一次肠道水疗;检测患者的血淀粉酶、内毒素和肿瘤坏死因子(TNF)-α。结果:急性胰腺炎患者血淀粉酶、内毒素和TNF-α均显著高于正常。与对照治疗组相比,治疗组血清淀粉酶、内毒素和TNF-α的下降趋势显著增快。结论:肠道水疗可促进急性胰腺炎患者恢复。清除内毒素,促进肠道的运动。改善毒素症是其可能的机制。

Objective: To explore the effect and mechanism of whole gut washout on acute pancreatitis in human. Methods: Except the routine therapy, the patients were given whole gut washout e. o. d. in the therapy group. The amylase in blood, endotoxin and TNF-α on the first, third, fifth, seventh and fourteenth day in both groups were measured. Results: The amylase in blood, endotoxin and TNF-α in both therapy groups were much more higher than that of normal control groups. In the therapy group, the amylase in blood, endotoxin and TNF-α deceased more quickly than that of control therapy group. The patients also recuperated more quickly than the control therapy group. Conclusion: Whole gut washout can inhibit the progression of acute pancreatitis, clear away the endotoxin, promote the motility of gut, amelioratea copremia.