原发性高血压患者左室肥厚伴劳损的临床意义与随访

CLINICAL SIGNIFICANCE AND FOLLOW-UP OF LEFT VENTRICULAR HYPERTROPHY AND STRAIN IN PATIENTS WITH ESSENTIAL HYPERTENSION

本文对48例左室肥厚伴劳损的原发性高血压患者进行了长期随访观察,并与48例不伴有左室肥厚及劳损患者作对照。结果证寒:(1)左室肥厚伴劳损组(Ⅰ组)的运动诱发ST段压低、心绞痛和心肌梗塞的发生率明显高于无左室肥厚伴劳损组(Ⅱ组)(P<0.001),(2)24小时动态心电图监测显示,Ⅰ组室性心律失常的发生率高于Ⅱ组(P<0.01),(3)Ⅰ组随访病死率明显高于重组(P<0.001)。因此,左室肥厚伴劳损是原发性高血压患者的一项危险因素。

A long-term follow-up study was done in 96 patients with essential hypertension, including 48 cases with left ventricular hypertrophy and strain, and 48 cases without. The results showed that (1) The presence of left ventricular hypertrophy and strain (Croup Ⅰ) had significantly more episodes of exercise-induced ST segment depression angina and myocardial infarction than those without (Croup Ⅱ) (p<0.001); (2) 24 h ambulatory electrocardiogram detected more ventricular ectopic beats and nonsustained vontricular tachycardia in Croup Ⅰ than in Group Ⅱ; (3)long-term follow-up showed that mortality rate was 27.08％ in Group Ⅰ,8.33％ in Group Ⅱ (p<0.001). Thus, left ventricular hypertrophy and strain is a risk factor for patients with essential hypertension.