涎腺腺样囊性癌的复发、转移及治疗初析

Recurrence,metastasis and treatment for salivary adenoid cystic carcinoma

目的 探讨影响涎腺腺样囊性癌的复发及转移的因素。方法 对 6 1例涎腺腺样囊性癌做临床病理分析。结果 临床分期晚期位于颌下腺、舌下腺肿瘤神经受侵率高 ,复发率高 ;肿瘤复发是死亡的主要原因 ;局部总复发率为 4 7.5 % ,远地转移率为 2 9.5 % ,颈淋巴结转移率为 9.8%。结论 复发率与发病部位、临床分期及治疗方法等相关 ,外科是主要的治疗方法 ,放射治疗可以有效地控制病变的发展。

Objective To study the factors influencing recurrence and metastasis of salivary adenoid cystic carcinoma (SACC). Methods Sixty one cases were followed up and studied on some factors influencing recurrence and metastasis in patients. Results SACC in the submandibular and sublingual glands was subject to recur,so did the SACC in advanced clinical stage(stageⅢ andⅣ),the more the nerve was involved,the more the tumor was to recur;tumor recurrence was the major factor of death;the overall local recurrent rate was 47.5%,distant metastasis rate was 29.5% and neck lymph node metastasis 9.8%. Conclusion Recurrence rate is related to tumor site,clinical stage and treatment methods. Surgery is the choice of treatment,radiotherapy may control the growth of the disease effectively.