生脉注射液对冠心病的疗效观察

Clinical Analysis of Shengmai Injection in the Treatment of Coronary Heart Disease

目的 观察生脉注射液对冠心病的疗效。方法 将冠心病患者 14 8例分成两组。对照组用硝酸甘油加入改良极化液中静点 ;观察组在对照组治疗的基础上 ,同时用生脉注射液 60ml溶入 5 %葡萄糖注射液 5 0 0ml中静脉滴注 ,每天 1次 ,共 7～ 10d。结果 观察组心力衰竭及心绞痛之显效率均明显高于对照组。而AMI ,两组显效率差异无显著意义 ,可能与样本较小有关。结论 生脉注射液具增强冠脉血流量 ,改善心肌缺血缺氧 ,降低血液黏度 ,抑制血栓形成的作用。亦能增强心肌收缩力 ,提高心输出量 ,改善左心功能 ,具有明显强心作用。临床验证用于治疗冠心病疗效确切、疗程短、安全 ,可作为治疗冠心病的重要辅助用药。

Objective To evaluate the mechanism of Shengmai injection(SMI) in the treatment of coronary heart disease(CHD).Methods 148CHD patients ,the treatment group(74 cases) were treated with SMI,60ml diluted in 500 ml of 5% glucose solution,intravenously dripped once daily for 7～10days.The control group (74cases) were treated with common therapy .The curative effect was observed.Results The total effective rate of heart failure and Angina pectoris in treatment group were obviously higher than that in control group.But the difference between the effective of AMI in two groups was not significant,perhaps it is in relation to less of samples.Conclusion It has been proven that SMI can accelerate the blood flow of coronary artery and cardiac muscle nutrition. Improve the ischemia and anoxia of cardiac muscular, reduce blood viscosity and inhibit thrombus formation,and also can improve cardiac contractility,elevate cardiac stroke volume,improve left ventricular function,and have obviously cardiotonic activities.It shows obvious effects of shorting therapeutic course,efficient and safe in treating CHD.It can be taken as an important auxiliary treatment for CHD.