无创通气治疗COPD并Ⅱ型呼衰28例

Treatment Effects of Noninvasive Ventilation on COPD Patients with TypeⅡRespiratory Failure

目的 探讨无创通气治疗慢性阻塞性肺疾病 (COPD)并 型呼衰的临床应用价值。方法 对 2 8例慢性阻塞性肺疾病 (COPD)并 型呼衰患者采用 Bi PAP呼吸机经口鼻面罩正压通气 ,观察治疗前后血气分析的p H、Pa O2 、Pa CO2 、Sa O2 指标变化。结果 无创通气后 Pa O2 、Sa O2 均明显升高 ,Pa CO2 明显降低 ,p H明显改善 ,差异均有显著性 (P<0 .0 1)。结论 Bi PAP呼吸机经口鼻面罩无创通气治疗慢性阻塞性肺疾病 (COPD)并 型呼衰疗效满意 ,无明显并发症 ,值得临床推广应用。

Objective To investigate the clinic significance using noninvasive ventilation on COPD with typeⅡ respiratory failure.Methods The blood gas parameters including pH, PaCO 2, PaO 2, SaO 2, before and after utilization of BiPAP ventilator (manufactured by Weikang company in the U.S.) were observed in the mode of positive airway pressure ventilation via nasal and facial mask in 28 patients with COPD complicating typeⅡ respiratory failure. Results The values of both of PaO 2 and SaO 2 greatly increased, the value of PaCO 2 greatly decreased, and the value of pH improved significantly. The differences were statistically significant between before and after noninvasive ventilation.Conclusion Utilization of BiPAP ventilator via nasal and facile mask positive airway pressure ventilation has a satisfactory therapeutic effect, without obvious side effect. It deserves further study for a wider use.