小潮气量联合低水平PEEP机械通气治疗COPD呼衰并肺大泡

Low tidal volume and low level PEEP mechanical ventilation for COPD patients with respiratory failure and emphysematous bled of lung

目的 了解小潮气量联合低水平呼吸末正压通气 (PEEP)机械通气治疗慢性阻塞性肺疾病(COPD)呼衰并肺大泡的疗效及安全性。方法 48例COPD呼衰并肺大泡的病人随机分为常规通气组 2 3例和小潮气量联合低水平PEEP通气组 2 5例 ,比较两组的通气时间、气压伤发生率及死亡率。结果 小潮气量联合低水平PEEP组气压伤的发生率显著低于常规通气组 ,通气时间也显著小于常规通气组 ,死亡率的比较两组间差异无显著意义。结论 小潮气量联合低水平PEEP机械通气治疗COPD呼衰并肺大泡可显著减少病人气压伤的发生率和缩短通气时间 ,减少病人的精神、经济负担 。

ObjectiveTo study the effects and safety of low tidal volume and low level PEEP mechanical ventilation for COP D patients with respiratory failure and emphysematous bled of lung.Metho dsFourty-eight COPD patients with respiratory failure and emphysemato us bled of lung were divided into routine ventilation group (group Ⅰ n =23) and low tidal volume and low level PEEP ventilation group (group Ⅱ n=25).The mortality and complications between the two groups were compared.ResultsThe incidence of pneumothorax in group Ⅱ was lower than that in group Ⅰ significantly.The period of ventilation in gr oup Ⅱ was shorter than that in group Ⅰ significantly.ConclusionLow tidal volume and low level PEEP mechanical ventilation is a safe and effe ctive method for COPD patients with respiratory failure and emphysematous bled o f lung.It could reduce lung injury caused by ventilator and shorten ventilation time.It was valuable for spreading use clinically.