摘要
吗吲哚(mazidol)化学名为5-(4-氯苯基)-2,5-二氯-3H-咪唑骈[2,12]异吲哚-5醇,是近年来合成的食欲抑制药,具有减肥等功效。它在国外已批量生产,美国药典(ⅩⅫ)也有收载。目前国内正在研制,准备生产。
The present paper deals with derivative spectroscopic method used for the determination of mazidol tablet. The calibration curve was linear in the range of 5-15 μg /ml (r=0.9997). Recovery from tablet was 100.9%±0.85% (CV, n=10). The proposed method is simple and rapid without any preliminary separation. The results obtained are satisfactory both in recovery and in precision.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1992年第6期379-381,共3页
Journal of China Pharmaceutical University
关键词
导数光谱法
吗吲哚
Derivative UV Spectroscopic
Mazidol
