婴幼儿反复上呼吸道感染与佝偻病相关性探讨

THE RELATIONSHIP BETWEED UPPER RESPIRATORY INFECTION ADN RICHETS IN INFANTS

目的 :探讨婴幼儿反复上呼吸道感染与佝偻病的关系。方法 :对 2 0 0 0年 1月至 2 0 0 2年7月门诊就诊的 14 3例反复上呼吸道感染婴幼儿和 173例对照组婴幼儿进行骨碱性磷酸酶(BALP)检测 ,结果研究组BALP阳性 6 7例 (4 6 .85 % ) ,可疑阳性 2 4例 (16 .78% ) ,对照组BALP阳性 33例 (19.0 7% ) ,可疑阳性 2 6例 (15 .0 3% ) ,反复上呼吸道感染组佝偻病患病率明显高于对照组(P <0 .0 1) ,使用维生素D及钙剂治疗佝偻病及可疑佝偻病患儿 ,并进行半年随访。结果 :在反复上呼吸道感染组婴幼儿中未发生上呼吸道感染 4 3例 (4 7.2 3% ) ,发生 (1～ 2 )次为 34例 (37.36 % ) ,上呼吸道感染的患病率比治疗前明显减少。结论

Objective:To study the relation between the repeatedly upper respiratory infection and the rickets.in infants. Methods: The level of bone alkaline phosphatase (BALP) was examined in 143 infants with upper respiratory tract infection repeatedly (test group) and the 173 infants as control group in out-patient clinic. Results: The test group had 67 positive BALP (46.85%) and 24 suspicious positive (16.78%), the control group had 33 positive BALP (19.07%) and 26 suspicious positive (15.03%). The rickets prevalence rate in the test group was markedly higher than that in the control group ( P <0.01). After half a year to administrate the vitamin D and the calcium, the 43 infants (47.23%) did not catch the upper respiratory infection and the 34 infants ( 37.36% ) catch it one or two times at least in the test group. The prevalence rate of upper respiratory infection in the infants had been treated was markedly reduced than that in infants without treatment. Conclusion: There is intimate clinical correlation between the repeated upper respiratory infection and the rickets in infants.