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非聚丙烯酰胺凝胶电泳(Non-PAGE)的复杂蛋白质组表达分析:一种新的二维液相技术用于完整蛋白质的高通量分离分析 被引量:2

Drug Discovery Non-PAGE Complex Protein Expression Analysis Tutorial:A 2-D Liquid-Phase Technique for High-Throughput Analysis of Inteact Proteins
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摘要 揭示基因组-转录子组-蛋白质组(Genome-transcriptome-proteome)的关系、描绘蛋白质翻译后修饰(PTM)的途径、常规地运用质谱(MS)技术进行蛋白质的定性和识别,这三方面的力量和需求将推动日后的新药开发.在过去的几年里,蛋白质定性和蛋白质组学研究的突飞猛进有赖于这三方面发展的相结合,这种整合成为生物技术研发(R&D)工作流程的一个典范.正如人类基因组计划的经验,研究生物相关体系中的复杂蛋白的表达同样亟待新的分析技术和手段.
机构地区 Eprogen公司
出处 《生命科学仪器》 2004年第2期19-21,共3页 Life Science Instruments
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