盐酸索他洛尔合成工艺条件的分析与优化

Study on Selection of Synthetic Condition of Sotalol hydrochloride by Orthogonal Test

本文利用正交实验方法系统地研究了合成盐酸索他洛尔过程中各工艺参数对产品收率的影响 ,得到了最佳工艺条件 ,在此条件下 ,盐酸索他洛尔的收率可达 80

The effects of technical conditions of directive rate sotalol hydrochloride synthesis is process on rare sotalol recovery were systematically studied by orthogonal test.The optimum technical conditions have been found and the recovery of rare sotalol could reach 80% under the conditions.