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高张盐水休克复苏过程的免疫调节作用 被引量：2

Immunomodulatory Effect of Hypertonic Saline in Shock Resuscitation
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摘要 高张盐水(HTS)用于严重创伤性和失血性休克病人的紧急复苏,有助于迅速恢复血容量和改善血流动力学,同时具有减轻休克引发的炎症反应和免疫抑制。综述HTS复苏过程对炎症和免疫的调节作用。
作者 柳垂亮 招伟贤 萧广钧
机构地区 广州中医药大学第二附属医院麻醉科 第一军医大学珠江医院麻醉科
出处 《国外医学（麻醉学与复苏分册）》 2004年第2期92-95,共4页 Foreign Medical Sciences(Anesthesilolgy and Resuscitation)
关键词 高张盐水 休克 复苏 免疫调节作用 炎症反应 免疫抑制
分类号 R605.971 [医药卫生—急诊医学]
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参考文献17

  • 1Hirsh M, Dyugovskaya L, Bashenko Y, et al. Reduced rate of bacterial translecation and improved variables of natural killer cell and T-cell activity in rats surviving controlled hemorrhagic shock and treated with hypertonic saline. Crit Care Med,2002,30(4
  • 2Ciesla DJ, Moore EE, Biffl WL, et al. Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotouicity and reestablished by repeated hypertonic challenge. Surgery, 2001, 129(5): 567-575.
  • 3Sun LL, Ruff P, Austin B, et al. Early up-regulation of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression in rats with hemorrhagic shock and resuscitation. Shock, 1999,11(6) :416-422.
  • 4Angle N, Hoyt DB, Coimbra R, et al. Hypertonic saline resuscitation diminishes lung injury by suppressing neutrophil activation after hemorrhagic shock. Shock, 1998,9 (3): 164-170.
  • 5Coimbra R, Junger WG, Hoyt DB, et al. Hypertonic saline resuscitation restores hemorrhage-induced immuniosuppression by decreasing prostaglandin E2 and interleukin-4 production. J Surg Res, 1996,64:203-209.
  • 6Oreopoulos GD, Hamilton J, Rizoli SB, et al. In vivo and in vitro modulation of intercellular adhesion molecule (ICAM)-1 expression by hypertonicity. Shock,2000,14(3) :409-414.
  • 7Ciesla DJ, Moore EE, Musters RJ, et al. Hypertonic saline alteration of the PMN cytoskeleton: implications for signal transduction and the cytotoxic response. J Trauma,2001,50(2) :206-212.
  • 8Rizoli SB, Kapus A, Parodo J, et al. Hypertouic immunomodulation is reversible and accompanied by changes in CDllb expression. J Surg Res,1999,83(2): 130-135.
  • 9Coimbra R, Junger WG, Liu FC, et al. Hypertonic/hyperoncotic fluids reverse prostaglandin E2 (PGE2)-induced T-cell suppression. Shock, 1995,4( 1 ) :45-49.
  • 10Oreopoulos GD, Bradwell S, Lu Z, et al. Synergistic induction of IL-10by hypertonic saline solution and lipopolysaccharides in murine peritoneal macrophages. Surgery,2001,130(2): 157-165.

同被引文献21

  • 1冷静,彭韬,冯振卿,钱玲梅,王笑云.大鼠肾缺血再灌注后肾小管上皮细胞凋亡的研究[J].江苏医药,1998,24(12):865-867. 被引量：5
  • 2龚华渠,杨天德,陶军.高渗盐水对缺血再灌注损伤肾组织髓质过氧化酶活性的影响[J].重庆医学,2006,35(6):519-520. 被引量：3
  • 3张春海,夏照帆.烧伤休克延迟复苏的研究进展[J].实用医药杂志,2007,24(1):93-95. 被引量：6
  • 4陈新龙,刘洪琪,邢玉玺,侯志成,陈志勇,李德水,刘凌风.小剂量高渗盐胶体复苏烧伤休克的临床研究[J].武警医学院学报,2007,16(3):239-241. 被引量：5
  • 5夏照帆,方之扬.烧伤休克.见:黎鳌,扬宗城.黎鳌烧伤学[M].上海:上海科学技术出版社,2001.38
  • 6Maybauer,Dirk M,Mavbauer et al.Resuscitation with hypertonic saline in burn shock shock and sepsis[J].Critical Care Medicine,2006,34(6):1844
  • 7Oda J,Ueyama M,Yamashita K et al.Hypertonic lactated saline resuscitation reduces the risk of abdominal compartment syndrome in severely burned patients[J].J Trauma,2006,60(1):64.
  • 8Powers KA,Zurawska J,Szaszi K et al.Ilvpertonic resuscitalion of hemorrhagic shock prevents alveolar macrophage activation by preventing systemic oxidative stress due to gut schemi/reperfulion[J].Surgery,2005,137:66
  • 9Rizoli SB,Kapus A,Fan J,et al.Immunomodulatory effects of hypertonic resuscitation on the development of lung inflammation following hemorrhagec shock[J].J Immunol,1998,161(11):6288
  • 10Oreopoulos GD,Hamilton J,Rizli SB,et al.In vivo and in vitro modulation of intercellular adhesion molecule (ICAM)-1 expression by hypertonicity[J].Shock,2000,14(3):409

引证文献2

二级引证文献3

国外医学（麻醉学与复苏分册）
2004年 第2期

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