摘要
经气管灌注致癌物质(甲基胆蒽及二乙基亚硝胺)一段时间后,经食道灌注N—二环已胺磺酰氯(CSD),此抑癌组金地鼠71只没有发生肺癌;而单纯致癌组金地鼠72只中有8例产生肺癌。结果证明CSD有阻断癌变能力,为研制新的抗肿瘤药物提供了实验基础。
The suppressed tumor groups have not developed lung cancer with polyamine inhibitor CSD through esophagus after treatment of carcinogenous agents (MAC and DEN) through trachea, while the carcinogenous groups (MAC and DEN) have developed 8 cases of lung cancer. The result indicates that CSD may block carcinogenesis, It provides the experimental basis for preparing a new antitumor medicine.
出处
《中国医科大学学报》
CAS
CSCD
1992年第3期161-162,共2页
Journal of China Medical University
基金
卫生部科学研究资助
关键词
肺肿瘤
胺磺酰氯
抑制剂
chlorosulfonyl dicyclohexylamine (CSD)
block
experimental lung cancer
