慢性阻塞性肺疾病患者高碳酸血症与肺功能关系的探讨

HYPERCAPNIA AND PULMONARY FUNCTION IN CHRONIC OBSTRUCTIVE LUNG DISEASE

对伴有和不伴有高碳酸血症两组(每组21名)COPD患者进行肺功能测定井对比分析。结果:伴有高碳酸血症组的VT、VC、%VC、FEV_1、MVV、%MVV,V_(50)/V_(25)、V_(25)/H明显低于不伴有高血碳酸血症组(P<0.01)。fR明显增多(P<0.01),FEV_1、%DLCO、FRV、RV两组无明显差异(P>0.05);VT在0.45L以下,VC1.5L以下,FEV_1在1L以下,fR在23次/min以上时PaCO_2增高。

Pulmonary function tests in 21 hypercapnic patients (group A) and 21 normocapnic patients (group B) with chronic obstructive lung disease were studied. (1) Group A were significantly decreased, VC, %VC, FEV_1,MVV,VT, MVV%,V_(50)/V_(25) and V_(25)/H, and the fR were significantly increased.There are no statistically significantce between two groups in PaO_2, FEV%, DLco FRV or RV. (2) If the VC is less than 0.5L or the FEV_1 lees than 0.8L or the VT less than 0.45L or fR more than 23/min they are almost hypercapnia in patients with COPD.